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Symbol Name ID |
Birc3
baculoviral IAP repeat-containing 3 MGI:1197007 |
| Darker colors indicate more annotations |
| Human Phenotypes | Subacute progressive viral hepatitis |
| Disease(s) Associated with BIRC3 | |
| hepatocellular carcinoma |
| Mouse Phenotypes | decreased B cell apoptosis |
increased B cell proliferation |
increased T cell proliferation |
decreased immature B cell number |
abnormal leukocyte cell number |
abnormal lymphocyte cell number |
decreased follicular B cell number |
increased marginal zone B cell number |
increased B cell number |
increased T cell number |
decreased macrophage cell number |
increased IgA level |
decreased IgG1 level |
increased IgG3 level |
increased IgM level |
abnormal T cell physiology |
abnormal macrophage physiology |
abnormal gut-associated lymphoid tissue morphology |
enlarged mesenteric lymph nodes |
lymph node hyperplasia |
abnormal immune cell physiology |
abnormal cytokine secretion |
increased interferon-gamma secretion |
abnormal interleukin-1 beta secretion |
abnormal interleukin-12 secretion |
abnormal tumor necrosis factor secretion |
decreased susceptibility to endotoxin shock |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||
| Birc3tm1Jda/Birc3tm1Jda | ||||||||||||||||||||||||||||
| Birc3tm1Rgk/Birc3tm1Rgk | ||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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